A further 1,978 cases of Covid-19 have been confirmed in the Republic.
On Friday morning, there were 221 Covid patients in hospital, including 43 in intensive care units.
Deputy chief medical officer Dr Ronan Glynn said 10,000 new cases have been reported over the last week.
“While we have very high incidence across Donegal, Monaghan, Mayo, Galway, Roscommon, Louth and Cavan in particular, incidence is rising across all 26 counties,” he said.
“In addition, while incidence is particularly high in those aged 16-29 years, incidence is now rising across all age groups.
“While vaccination has very positively impacted on the proportion of positive cases who end up in hospital or critical care, the current high and increasing incidence will nevertheless result in a significant number of people getting very sick with Covid-19.”
It comes as the latest figures show that Ireland has one of the highest Covid infection rates in the European Union - and after the Department of Public Health West today urged people in Mayo to continue to follow public health advice this weekend due to concerns over a rapid increase in Covid-19 cases in Mayo in recent weeks.
The latest figures, covering the 14-day incidence during 27/7/2021 to 10/08/2021, reported Mayo with an incidence rate of 672.8 cases per 100,000 of population. This compares to a national incidence rate of 431.8/100,000 of population. Westport and Swinford are the third and fourth worst-hit electoral areas in the entire country but the Department of Public Health West has seen significant increases in Claremorris, Castlebar and Ballina areas also.
Fresh data from the European Centre for Disease Prevention and Control show that Ireland has a 14-day incidence rate of 392 cases per 100,000.
Only Cyprus (931 per 100,000), Spain (604) and France (462) have a higher rate of infection than Ireland within the EU.
Northern Ireland and the Border region are also among the most Covid-infected regions in Europe.